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Table 1.  Pharmacological compounds used in early treatment studies of experimentally-infected animals.

 

Compounds listed in boldface type prolonged incubation periods of infected animals.

 

Anti-virals         

Amantidine                   

Adenine arabinoside

Cytosine arabinoside

Isoprinosine

Methisazone

Phosphonoacetic acid

Rifampicin

Sodium butyrate

Sodium thiocyanate

Thiamphenicol

Virazole

 

Anti-fungals

            Amphotericin B

            MS-8209

            Griseofulvin

Sinefungin

 

Anti-protozoals

            Chloroquin                    

            Glycobiarsol

Metronidazole

                       

Anti-helminthic

            Niclosamide

 

Anti-bacterials

            Rifampicin

Sulfamethoxizole

            Tetracylcline

            Trimethoprin

            Thiamphenicol

 

Polyanions

Carrageenan

Chondroitin sulfate

Dextran sulfate

Heparan sulfate

HPA-23

Pentosan polysulfate

Polyvinyl sulfate

Silicotungstate

                       

 

Lymphoreticular blockers

            Silica                                       

            Trypan blue

 

Interferon and interferon inducers

Newcastle disease virus

            PolyI:Poly C                             

            Sendai virus                              

Statolon

Tilorone HCl      

                                               

Immunostimulants                                 

            Bacterial polysaccharide

BCG                                        

Phytohemagglutinin       

Vaccinial virus

                                   

Immunosuppressants                

            Antilymphocytic serum  

Arachis oil                                

Steroids                                                                       

Antineoplastics                         

            Actinomycin D              

Cyclophosphamide                    

Methotrexate                

Streptozotocin                                                  

Hormones                    

            Adrenalin

            Estradiol

            Insulin

Prednisone

            Propylthiouracil

            Testosterone

                       

Miscellaneous                          

            Colchicine                    

            Chlorpromazine

            DEAE-dextran              

            Neutral dextran

            Ouabain

Vitamin C

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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